Wall Street Week Ahead: Attention turns to financial earnings

NEW YORK (Reuters) - After over a month of watching Capitol Hill and Pennsylvania Avenue, Wall Street can get back to what it knows best: Wall Street.

The first full week of earnings season is dominated by the financial sector - big investment banks and commercial banks - just as retail investors, free from the "fiscal cliff" worries, have started to get back into the markets.

Equities have risen in the new year, rallying after the initial resolution of the fiscal cliff in Washington on January 2. The S&P 500 on Friday closed its second straight week of gains, leaving it just fractionally off a five-year closing high hit on Thursday.

An array of financial companies - including Goldman Sachs and JPMorgan Chase - will report on Wednesday. Bank of America and Citigroup will join on Thursday.

"The banks have a read on the economy, on the health of consumers, on the health of demand," said Quincy Krosby, market strategist at Prudential Financial in Newark, New Jersey.

"What we're looking for is demand. Demand from small business owners, from consumers."

EARNINGS AND ECONOMIC EXPECTATIONS

Investors were greeted with a slightly better-than-anticipated first week of earnings, but expectations were low and just a few companies reported results.

Fourth quarter earnings and revenues for S&P 500 companies are both expected to have grown by 1.9 percent in the past quarter, according to Thomson Reuters I/B/E/S.

Few large corporations have reported, with Wells Fargo the first bank out of the gate on Friday, posting a record profit. The bank, however, made fewer mortgage loans than in the third quarter and its shares were down 0.8 percent for the day.

The KBW bank index <.bkx>, a gauge of U.S. bank stocks, is up about 30 percent from a low hit in June, rising in six of the last eight months, including January.

Investors will continue to watch earnings on Friday, as General Electric will round out the week after Intel's report on Thursday.

HOUSING, INDUSTRIAL DATA ON TAP

Next week will also feature the release of a wide range of economic data.

Tuesday will see the release of retail sales numbers and the Empire State manufacturing index, followed by CPI data on Wednesday.

Investors and analysts will also focus on the housing starts numbers and the Philadelphia Federal Reserve factory activity index on Thursday. The Thomson Reuters/University of Michigan consumer sentiment numbers are due on Friday.

Jim Paulsen, chief investment officer at Wells Capital Management in Minneapolis, said he expected to see housing numbers continue to climb.

"They won't be that surprising if they're good, they'll be rather eye-catching if they're not good," he said. "The underlying drive of the markets, I think, is economic data. That's been the catalyst."

POLITICAL ANXIETY

Worries about the protracted fiscal cliff negotiations drove the markets in the weeks before the ultimate January 2 resolution, but fear of the debt ceiling fight has yet to command investors' attention to the same extent.

The agreement was likely part of the reason for a rebound in flows to stocks. U.S.-based stock mutual funds gained $7.53 billion after the cliff resolution in the week ending January 9, the most in a week since May 2001, according to Thomson Reuters' Lipper.

Markets are unlikely to move on debt ceiling news unless prominent lawmakers signal that they are taking a surprising position in the debate.

The deal in Washington to avert the cliff set up another debt battle, which will play out in coming months alongside spending debates. But this alarm has been sounded before.

"The market will turn the corner on it when the debate heats up," Prudential Financial's Krosby said.

The CBOE Volatility index <.vix> a gauge of traders' anxiety, is off more than 25 percent so far this month and it recently hit its lowest since June 2007, before the recession began.

"The market doesn't react to the same news twice. It will have to be more brutal than the fiscal cliff," Krosby said. "The market has been conditioned that, at the end, they come up with an agreement."

(Reporting by Gabriel Debenedetti; editing by Rodrigo Campos)

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Mali Government Is Left Reeling After Islamists Take Village Long Held by Army

DAKAR, Senegal — Islamists advanced into territory held by the Mali government on Thursday, overrunning a long-held defensive position in the center of the country and dealing a significant blow to the Malian Army in its attempt to contain the militants who have seized the nation’s north, according to a Malian Army officer.

Over the last two days, clashes have erupted between the army and militants around Konna, a sleepy mud-brick village that for months had marked the outer limit of the Malian Army’s control after it lost half of the country to Islamists and their allies last April.

On Thursday, though, the town appeared to have fallen to the Islamists, forcing Mali’s army to retreat and inflicting losses on it. The Malian officer, reached by phone in Bamako, the capital, was categorical, confirming the loss of Konna and calling the situation “critical” for the Malian Army.

“It’s a very serious situation, very dangerous,” said the officer, who was not authorized to speak publicly.

The Islamists now threaten a major airfield some 25 miles away at the town of Sévaré, which is also the home of a significant army base. And 10 miles from Sévaré is the historic river city of Mopti, the last major town controlled by the Malian government, with a population of more than 100,000.

“There were hard fights, but we lost,” the officer said.

“The Malian Army has retreated to Sévaré,” he said. “We need the help of everybody to save Sévaré.”

A spokesman for the Islamists, Sanda Ould Boumana, said from rebel-held Timbuktu: “We have taken the town of Konna. We control Konna, and the Malian Army has fled. We have pushed them back.”

The army’s official spokesman, Lt. Col. Diarran Kone, refused to confirm or deny the loss of the village. Gen. Carter F. Ham, the commander of the Pentagon’s Africa Command, who was traveling in neighboring Niger on Thursday, said that he had seen the reports from Mali but could not yet independently verify them.

“If true, this is a significant change in the situation,” General Ham said.

This week’s clashes were the first time that the two sides had fought since Islamists and their Tuareg rebel allies conquered the north of Mali last spring, splitting the country in two and leaving the Malian Army in disarray.

For months, the United Nations and Mali’s neighbors have been debating and planning a military campaign to retake the north by force, if necessary, an international push that is supposed to be led by Malian forces. Analysts had previously said that the outcome of this week’s fighting at Konna would be a significant indicator of the army’s fitness to undertake the reconquest of the north.

Its loss now raises serious questions about the plan, tentatively approved by the United Nations Security Council last month. A retooled Malian Army was to be the plan’s centerpiece, aided by troops from around the region.

The rebel advance prompted the Security Council to meet Thursday night in an emergency session on the deteriorating situation. Afterward it issued a statement expressing “grave concern” as well as determination to enforce previous resolutions on ending the crisis, including the dispatching of an African-led force to help the government reclaim lost territory.

France’s ambassador to the United Nations, Gérard Araud, who had called for the meeting, confirmed that Mali’s interim president, Dioncounda Traore, had sent a letter to President François Hollande of France and the president of the Security Council seeking help in countering the Islamists’ latest advance.

Mr. Hollande said on Friday he was ready to respond to Mali’s appeal for assistance, The Associated Press reported. He said France would seek a United Nations resolution for action but that it was “ready to stop the terrorists’ advance if it continues.”

The loss of Konna could add urgency to Western preparations — France and to some extent the United States have pledged assistance — aimed at extinguishing the quasi-state of militants. Many of them belong to, or are affiliated with, Al Qaeda in the Islamic Maghreb, which controls a vast portion of territory in West Africa.

Reporting was contributed by Eric Schmitt from Niamey, Niger, Cheick Diouara from Accra, Ghana, Rick Gladstone from New York, and Richard Berry from Paris.

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Holiday sales of PCs slide for first time in five years: IDC

SEATTLE (Reuters) – Holiday season sales of personal computers fell for the first time in more than five years, according to tech industry tracker IDC, as Microsoft Corp’s new Windows 8 operating system failed to excite buyers and many opted for tablet devices and powerful smartphones instead of PCs.

PC makers such as Hewlett-Packard Co, Lenovo Group and Dell Inc sold 89.8 million PCs worldwide in the fourth quarter of last year, down 6.4 percent from the same quarter of 2011. That was slightly worse than expected by most.

For all of 2012, 352 million PCs were sold, down 3.2 percent from 2011. That was the first annual decline since 2001, according to IDC. (Reporting By Bill Rigby; Editing by Gary Hill)

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Audrey Hepburn: Remembering the Private Legend

By Elizabeth McNeil

01/10/2013 at 07:35 PM EST

Audrey Hepburn with her son, Luca Dotti, in 1985

Audrey Hepburn Childrens Fund

She captivated the world with her doe-eyed beauty, but behind the Givenchy glamour, there was an Audrey Hepburn few people knew.

She thought her nose too big, her feet too large and her neck too long. She loved to shop for groceries (but not clothes), didn't wear makeup at home, never went to the gym and enjoyed two fingers of Scotch every night. 

"She was not this ethereal creature," says Robert Wolders, 76, the Dutch actor who was her companion for the last 13 years of her life. "She was an earthy woman with a ribald sense of humor."

What Hepburn had, adds Wolders, "was more than beauty. It was this extraordinary mystique."

Hepburn left Hollywood at age 34 at the height of her fame, moving into a 1732 farmhouse in Tolochenaz, a small Swiss village, where she found happiness raising two sons and purpose in her charity work for UNICEF. 

Two decades after her death from abdominal cancer at 63 on Jan. 20, 1993, her children and her last love remember the Audrey they adored. 

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Flu season strikes early and, in some places, hard

NEW YORK (AP) — From the Rocky Mountains to New England, hospitals are swamped with people with flu symptoms. Some medical centers are turning away visitors or making them wear face masks, and one Pennsylvania hospital set up a tent outside its ER to deal with the feverish patients.

Flu season in the U.S. has struck early and, in many places, hard.

While flu normally doesn't blanket the country until late January or February, it is already widespread in more than 40 states, with about 30 of them reporting some major hot spots. On Thursday, health officials blamed the flu for the deaths of 20 children so far.

Whether this will be considered a bad season by the time it has run its course in the spring remains to be seen.

"Those of us with gray hair have seen worse," said Dr. William Schaffner, a flu expert at Vanderbilt University in Nashville.

The evidence so far points to a moderate season, Schaffner and others say. It looks bad in part because last year was unusually mild and because the main strain of influenza circulating this year tends to make people sicker and really lay them low.

David Smythe of New York City saw it happen to his 50-year-old girlfriend, who has been knocked out for about two weeks. "She's been in bed. She can't even get up," he said.

Also, the flu's early arrival coincided with spikes in a variety of other viruses, including a childhood malady that mimics flu and a new norovirus that causes vomiting and diarrhea, or what is commonly known as "stomach flu." So what people are calling the flu may, in fact, be something else.

"There may be more of an overlap than we normally see," said Dr. Joseph Bresee, who tracks the flu for the Centers for Disease Control and Prevention.

Most people don't undergo lab tests to confirm flu, and the symptoms are so similar that it can be hard to distinguish flu from other viruses, or even a cold. Over the holidays, 250 people were sickened at a Mormon missionary training center in Utah, but the culprit turned out to be a norovirus, not the flu.

Flu is a major contributor, though, to what's going on.

"I'd say 75 percent," said Dr. Dan Surdam, head of the emergency department at Cheyenne Regional Medical Center, Wyoming's largest hospital. The 17-bed emergency room saw its busiest day ever last week, with 166 visitors.

The early onslaught has resulted in a spike in hospitalizations. To deal with the influx and protect other patients from getting sick, hospitals are restricting visits from children, requiring family members to wear masks and banning anyone with flu symptoms from maternity wards.

One hospital in Allentown, Pa., set up a tent this week for a steady stream of patients with flu symptoms. But so far "what we're seeing is a typical flu season," said Terry Burger, director of infection control and prevention for the hospital, Lehigh Valley Hospital-Cedar Crest.

On Wednesday, Boston declared a public health emergency, with the city's hospitals counting about 1,500 emergency room visits since December by people with flu-like symptoms.

All the flu activity has led some to question whether this year's flu shot is working. While health officials are still analyzing the vaccine, early indications are that it's about 60 percent effective, which is in line with what's been seen in other years.

The vaccine is reformulated each year, based on experts' best guess of which strains of the virus will predominate. This year's vaccine is well-matched to what's going around. The government estimates that between a third and half of Americans have gotten the vaccine.

In New York City, 57-year-old Judith Quinones skipped getting a flu shot this season and suffered her worst case of flu-like illness in years. She was laid up for nearly a month with fever and body aches. "I just couldn't function," she said.

But her daughter got the vaccine. "And she got sick twice," Quinones said.

Europe is also suffering an early flu season, though a milder strain predominates there. Flu reports are up, too, in China, Japan, the West Bank, the Gaza Strip, Algeria and the Republic of Congo. Britain has seen a surge in cases of norovirus.

On average, about 24,000 Americans die each flu season, according to the CDC. That's an estimate — the agency does not keep a running tally of adult flu deaths each year, only for children. Some state health departments do keep count, and they've reported dozens of flu deaths so far.

Flu usually peaks in midwinter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhea, and some develop pneumonia or other severe complications.

Most people with flu have a mild illness and can help themselves and protect others by staying home and resting. But people with severe symptoms should see a doctor. They may be given antiviral drugs or other medications to ease symptoms.

Flu vaccinations are recommended for everyone 6 months or older. Of the 20 children killed by the flu this season, only two were fully vaccinated.

___

AP Medical Writer Maria Cheng in London contributed to this report.

___

Online:

CDC flu: http://www.cdc.gov/flu/index.htm

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Stock index futures point to flat open

LONDON (Reuters) - Stock index futures indicated a flat-to-slightly lower open on Wall Street on Friday, with some traders citing nervousness ahead of results from financial group Wells Fargo due later in the day.

Futures for the S&P 500 and Nasdaq 100 were flat by 04.30 EST, while futures for the Dow Jones were 0.1 percent lower.

"There's maybe a little bit of nervousness ahead of Wells Fargo's results," said Darren Easton, director of trading at London-based firm Logic Investments.

Boeing Co's 787 Dreamliner jet suffered a cracked cockpit window and an oil leak on separate flights in Japan on Friday - the latest in a series of incidents to test confidence in the sophisticated new aircraft.

Infosys Ltd posted flat third-quarter net profits, beating analyst expectations, as the second-largest Indian software services provider maintained margins despite higher operating costs. It also raised revenue forecast for the full year to end March.

Credit card company American Express Co said it would cut about 5,400 jobs, or 8.5 percent of its workforce, as it restructures its business and pays legal bills.

SAC Capital Advisors expects client withdrawals of at least $1 billion in 2013 as the hedge fund battles intense regulatory scrutiny over insider trading allegations, the Wall Street Journal reported on Friday.

Unsecured creditors of MF Global Holdings Ltd on Thursday proposed a liquidation plan that could pay the brokerage's former customers in full.

Exxon Mobil Corp reported flaring at its 344,500 barrel-per-day (bpd) Beaumont, Texas, refinery, according to a message posted on a community information line.

Tycoon Carlos Slim's retail unit said it plans to relist on the Mexican stock exchange, offering a 15.2 percent stake to raise some $720 million to fund expansion plans, including possible acquisitions.

Supervalu Inc struck a $3.3 billion deal to reduce its burdensome debt by selling five of its supermarket chains to an investor group led by Cerberus Capital Management LP .

The Federal Reserve's policy of zero interest rates and asset purchases is appropriate and perhaps even insufficient, said Narayana Kocherlakota, president of the Minneapolis Fed.

European shares were flat on Friday although the pan-European FTSEurofirst 300 index <.fteu3> remained within sight of two-year highs.

Asian shares and Brent crude futures fell as a pick-up in Chinese inflation prompted profit taking, although an improving outlook for global economies curbed losses.

U.S. stocks rose on Thursday and the S&P 500 <.spx> ended at a fresh five-year high as stronger-than-expected exports from China spurred optimism about global growth prospects.

The Dow Jones industrial average <.dji> gained 80.71 points, or 0.60 percent, to 13,471.22. The Standard & Poor's 500 Index rose 11.10 points, or 0.76 percent, to 1,472.12. The Nasdaq Composite Index <.ixic> added 15.95 points, or 0.51 percent, to 3,121.76.

(Reporting by Sudip Kar-Gupta; Editing by Susan Fenton)

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Many Afghan Ex-Insurgents Regret Laying Down Arms

MEHTAR LAM, Afghanistan — Eidi Mohammed, a former Taliban commander who recently renounced violence and sought amnesty under the Afghan government’s reconciliation program, has had another change of heart. Now he is thinking about rejoining his old comrades. Jobless and losing hope he will ever find work, Mr. Mohammed, 38, took his frustrations to provincial officials. They told him there was nothing they could do.

Parwiz/Reuters

Many Taliban militants handed over their weapons last March in Laghman Province as part of the Afghan government

Shah Marai/Agence France-Presse — Getty Images

An Afghan Local Police training exercise last month in Nangarhar Province. Violence remains high in hotbeds of the insurgency.

“The moment I feel like I can move, I will go back to the mountains, rearm myself and fight you again,” Mr. Mohammed, who is recovering from a recent gunshot wound to the leg caused by a clash with a police officer, recalled warning the governor, police chief and top security official of Badghis Province.

He is not alone. Interviews with more than a dozen former insurgents find a group embittered and torn about their choice to lay down their arms. Many are unable to work and often unable to return to their villages for safety reasons; most feel the government has cheated them.

“I am just counting the days before someone kills me,” said Akhtar Mohammad, a former Taliban commander in Oruzgan. “Every passing moment I feel regret for joining the peace process.”

Mr. Mohammad, who is from the south, where the insurgency is the deadliest, said the only thing he had to show for his decision to switch sides was the turban he had been given for his reintegration ceremony.

Two years into one of the most ambitious efforts to lure Taliban fighters off the battlefield, many Afghan and Western officials acknowledge that the results have been disappointing. Though the number of people claiming the amnesty has swelled in the past year, violence remains high in the hotbeds of the insurgency, where the program has struggled to take hold.

Of the roughly 6,100 participants so far, 80 percent come from the relatively peaceful north and west of the country, where the Taliban presence is thinnest. And even some of those fighters say their activity was more criminal than political or ideological, even though the program was designed to flip the most committed fighters.

Many onetime fighters say they were only loosely affiliated with the Taliban. Though widely thought of as a unified Islamic movement, the Taliban in reality consist of a shifting constellation of forces whose agendas sometimes line up. Many of the insurgents who have given up fighting said they were formerly of Hezb-e-Islami, a rival faction to the Taliban that has been losing power and influence in recent years.

Although some fighters have found employment, Western officials argue that the reintegration initiative was never meant to be a jobs program. It pays a modest stipend, about $100 to $200 monthly for the first three months, depending on the fighter’s rank. In theory, the former fighters can find work on development projects financed in their home villages, though many projects have failed to get off the ground.

In two years, the so-called High Peace Council has spent less than half of what officials hoped to spend in 2011 alone. Tight controls have stalled village development projects meant to employ the former insurgents in their communities. About $180 million of the $235 million the program was granted sits idle in Afghan coffers.

The officials running the program called it a work in progress that would improve over time. The importance of employment for former fighters is acknowledged as an important element of keeping them from picking up arms again.

“We’re working on ways to improve the effectiveness of the program,” said Paul Martin Mason, who oversees the reintegration program for the United Nations Development Program.

In the meantime, many former fighters are expressing second thoughts with their decisions. Having tired of endless fighting, Hazrat Mir, a former Taliban commander in Laghman, joined the government with 130 of his men last year.

With promises of jobs and land, Mr. Mir said, his men left their villages and turned in their weapons, a dangerous prospect given the threat from former comrades. The danger, it turned out, was made clear by an attack the day before their reintegration ceremony in which the Taliban killed Mr. Mir’s top deputy.

Sangar Rahimi contributed reporting from Mehtar Lam, and Taimoor Shah from Kandahar.

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Samsung sets sights on RIM’s corporate users

Now that Samsung (005930) has bested Apple in the consumer smartphone market, at least where shipment volume is concerned, the company is setting its sights on Research in Motion’s (RIMM) corporate user base. The company is investing heavily in enterprise devices that incorporate a higher level of security and reliability than consumers require. Various government agencies and corporations aren’t fully sold on RIM’s upcoming BlackBerry 10 operating system and are still unsure if will satisfy their needs. As a result, they have begun to explore alternatives for their employees.

[More from BGR: iPhone 5 now available with unlimited service, no contract on Walmart’s $ 45 Straight Talk plan]

“The enterprise space has suddenly become wide open,” Kevin Packingham, chief product officer for Samsung Mobile USA, said in an interview with Reuters. “The RIM problems certainly fueled a lot of what the CIOs are going through, which is they want to get away from a lot of the proprietary solutions.”

[More from BGR: CES has sadly become a complete waste of time]

The executive revealed that Samsung’s corporate market ambitions advanced after its flagship Galaxy S III smartphone gained various security certifications. He noted that companies “want something that integrates what they are doing with their IT systems,” and that “Samsung is investing in that area.” Packingham said that enterprise has been a focus of the company for a long time and its products have finally evolved enough to “really take advantage” of the market.

“We knew we had to build more tech devices to successfully enter the enterprise market,” he said. “What really turned that needle was that we had the power of the GS3.”

This article was originally published on BGR.com

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Sandra Bullock Honored at People's Choice Awards for New Orleans Support

By Alison Schwartz

01/09/2013 at 10:45 PM EST

Sandra Bullock at the People's Choice Awards

Jason Merritt/Getty

Sandra Bullock took home big honors for her work in the Big Easy Wednesday night.

The People's Choice Awards crowned the Oscar-winning actress the favorite humanitarian for her career-spanning philanthropic efforts, including her dedication to New Orleans's Warren Easton Charter High School

"I'm not at all being modest when I say I'm not doing anything compared to what they do on a daily basis," Bullock, 48, told the crowd gathered at Los Angeles's Nokia Theatre.

Just six months after Hurricane Katrina hit in 2005, the actress showed her support by adopting the school, which sustained $4 million in damages during the storm. She donated hundreds of thousands of dollars for renovations, telling PEOPLE years later that she "felt such a profound need to do something for them."

Her generosity helped the charter school – the first public high school for boys in Louisiana – afford renovations, new band uniforms, athletic equipment and a new health clinic in a city that's close to her heart. After all, she adopted her son, Louis, from New Orleans in 2010 and also has a home in the Garden District.

She pointed to the tireless dedication of the school's students, teachers and tough principal. "I've seen her," she joked. "Yeah, you don't want to go into that office."

Bullock then gave a shout-out to her son, who was sick as home, she said.

"[The students] compete, but they never cut each other down," she added. "And all that happens not because it's easy, but because they do not allow themselves any other option than to succeed."

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Retooling Pap test to spot more kinds of cancer

WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported encouraging signs that one day, there might be.

Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.

How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.

In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.

This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.

"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.

But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.

The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.

"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.

"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.

But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.

More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.

Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.

The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.

So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.

The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.

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